The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 26, 1991
Filed:
Sep. 29, 1988
Applicant:
Inventors:
Trevor M Penning, Springfield, PA (US);
Leslie J Askonas, Haddonfield, NJ (US);
Assignee:
Trustees of University of Pennsylvania, Philadelphia, PA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N / ; A01N / ; A01N / ; A61K / ; C07C / ; C07C / ;
U.S. Cl.
CPC ...
514506 ; 514534 ; 514548 ; 514550 ; 514562 ; 514563 ; 514565 ; 514567 ; 514628 ; 514658 ; 514825 ; 514916 ; 558 44 ; 558 47 ; 560 12 ; 560 13 ; 560 22 ; 560 25 ; 560 27 ; 560 29 ; 560 30 ; 560 34 ; 560 45 ; 560 47 ; 560 48 ; 562430 ; 562432 ; 562433 ; 562435 ; 562437 ; 562438 ; 562439 ; 562454 ; 564192 ; 564212 ; 564213 ;
Abstract
Compounds such as 1-(4-bromoacetamidobenzyl)-5-methoxy-2-methylindole-3-acetic acid, N-(4-bromoacetamidophenyl) anthranilic acid and N-(3-bromoacetamidophenyl) anthranilic acid function as irreversible ligands for nonsteroidal antiinflammatory drug (NSAID) and prostaglandin binding sites. It is therefore expected that these compounds, and analogs thereof, will have utility as anti-inflammatory drugs, as affinity labeling agents and as ligands for use in affinity chromatography.