The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 22, 1991
Filed:
Mar. 15, 1990
Applicant:
Inventors:
Robert K Anderson, Plainsboro, NJ (US);
Ann E DeCamp, N. Plainfield, NJ (US);
Alan T Kawaguchi, Berkeley Heights, NJ (US);
Anthony O King, Hillsborough, NJ (US);
Sander G Mills, Woodbridge, NJ (US);
Ralph P Volante, East Windsor, NJ (US);
Assignee:
Merck & Co., Inc., Rahway, NJ (US);
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07F / ; C07D / ;
U.S. Cl.
CPC ...
549214 ; 549292 ; 544 69 ; 544149 ; 544584 ; 544226 ; 544374 ; 546 14 ; 546206 ;
Abstract
This invention discloses novel intermediates and novel process for their preparation where said intermediates are useful for the preparation of 5-oxygenated derivatives (T) of lovastatin and analogs thereof at the 8-acyl side chain and 6-position of the polyhydronaphthyl ring. Said derivatives of lovastatin (T) and analogs thereof are useful in treating hypercholesterolemia and are disclosed in the U.S. Pat. No. 4,963,538. ##STR1##