The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 22, 1991
Filed:
Apr. 29, 1988
Applicant:
Inventors:
Alan R Fritzberg, Edmonds, WA (US);
Daniel S Wilbur, Edmonds, WA (US);
Ananthachari Srinivasan, Kirkland, WA (US);
Dennis W Wester, Lynnwood, WA (US);
Assignee:
Neorx Corporation, Seattle, WA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N / ;
U.S. Cl.
CPC ...
436501 ; 436547 ; 436548 ; 436804 ; 436819 ; 436518 ; 435188 ; 530387 ; 530402 ; 530405 ; 530408 ; 424-11 ;
Abstract
There is disclosed a process for minimally derivatizing a targeting protein with a radionuclide such that the predominant species of derivatized targeting protein contains one radionuclide group as a single radiolabeled ligand, and whereby the binding characteristics of the targeting protein are minimally affected. There is further disclosed ligands that can chelate a metal radionuclide or bind a halogen radionuclide while providing a means for separating radiolabeled ligand from unradiolabeled ligand.