The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 24, 1991
Filed:
Jan. 13, 1989
Applicant:
Inventors:
Heinrich H Peter, Binningen, CH;
Theophile Moerker, Fullinsdorf, CH;
Assignee:
Ciba-Geigy Corporation, Ardsley, NY (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07F / ; C07F / ; C07F / ;
U.S. Cl.
CPC ...
556148 ; 556-1 ; 556 41 ; 556 50 ; 556116 ; 556138 ; 556146 ;
Abstract
There is disclosed a process for the preparation of analytically pure chelate complexes which can be used in diagnostic medicine, for example as contrast media or radiopharmaceuticals. The process comprises transcomplexing a complex of a .beta.-dicarbonyl compound and a metal ion, for example a metal acetylacetonate, which is readily soluble in an organic solvent that is not miscible in all proportions with water, with a stoichiometric amount or with a less than equivalent amount of a chelating agent whose binding affinity for the metal ion is greater than that of the .beta.-dicarbonyl compound.