The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 10, 1991

Filed:

Jun. 30, 1987
Applicant:
Inventors:

Joan Petro, Cambridge, MA (US);

Jennifer Jackson, Reading, MA (US);

Scott Putney, Arlington, MA (US);

Assignee:

Repligen Corporation, Cambridge, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N / ; C12N / ; C12N / ; C12P / ; C12P / ;
U.S. Cl.
CPC ...
435 691 ; 435 697 ; 435 698 ; 435 688 ; 4352523 ; 43525233 ; 4353201 ; 536 27 ; 935 29 ; 935 48 ; 935 22 ; 935 73 ;
Abstract

The subject invention concerns a novel and superior recombinant DNA expression/secretion system for use in prokaryotic organisms to produce useful proteins. The system can be used to have proteins secreted by an engineered prokaryotic host where normally the proteins are not secreted by the host. Also, when using the expression system, proteins are expressed at much higher levels than when the expression system is not used.


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