The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 27, 1991

Filed:

Mar. 05, 1990
Applicant:
Inventors:

Alan Costello, Ashton Under Lyne, GB;

John D Jones, Bury, GB;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07C / ;
U.S. Cl.
CPC ...
558392 ;
Abstract

A process for the production of a substituted amide of the formula: ##STR1## where R.sup.1 is an optionally substituted aryl group, X.sup.1 is --O-- or --S-- and R.sup.2 is an optionally substituted alkyl, alkenyl, or alkynyl group or X.sup.1 R.sup.2 is an N-linked 5-membered nitrogen heterocycle comprising the halogenation, preferably bromination, in an inert solvent of a N-cyanomethyl-amide of the formula R.sup.1 --CONH.CH.sub.2 CN, followed by addition to the halogenated mixture, or to the mixture as halogenation is taking place, of a heterocyclic tertiary amine in a proportion of from about 1.0 to about 2.5 moles, and preferably from 1.3 to 2.1 moles, for each mole of halogen reacted, and finally treatment of the resulting quaternary salt with an alcohol, thiol or amine of the formula R.sup.2 X.sup.1 H.


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