The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 27, 1991
Filed:
Apr. 10, 1989
Applicant:
Inventor:
Kazuhide Yoshikawa, Yokohama, JP;
Assignee:
Tosoh Corporation, Shinnanyo, JP;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K / ; C07K / ; C12N / ;
U.S. Cl.
CPC ...
530399 ; 530412 ; 530419 ; 435 697 ;
Abstract
A process for the solubilization of a protein obtained via heterologous expression comprises the step of bringing the insoluble protein produced in transformed host cells into contact with an aqueous acid solution in the presence of a protein denaturant. The process also preferably comprises the further steps of elevating the pH value of the solution, by addition of alkali substance, and thereafter lowering the pH to obtain a biologically-active protein.
Quick Actions:
Yoshikawa, Kazuhide. (1991). Process for treating insoluble heterologous protein (U.S. Patent No. 5043430). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/5043430
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