The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 20, 1991

Filed:

Oct. 24, 1990
Applicant:
Inventors:

Keiichi Yokoyama, Iwakuni, JP;

Yoshio Noguchi, Waki, JP;

Noriaki Kihara, Iwakuni, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C / ; C07C / ;
U.S. Cl.
CPC ...
564215 ; 564186 ; 548342 ;
Abstract

Disclosed is a novel .alpha.-chloroketone derivative as a synthesis intermediate of N-cyano-N'-methyl-N'-(2-((5-methyl-1H-imidazol-4-yl)methylthio)ethyl)guani dine (general name: Cimetidine) which shows an action of controlling the secretion of gastric acid and is valuable as a medicine for remedy of a gastric ulcer. This .alpha.-chloroketone derivative is prepared by reacting disulfide derivative with sulfuryl chloride and reacting the reaction product with methylvinyl ketone or by reacting a mercapto derivative with 3-chloro-3-buten-2-one.


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