The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 13, 1991
Filed:
Apr. 05, 1990
Applicant:
Inventors:
James F Eggler, Groton, CT (US);
Eric R Larson, Groton, CT (US);
Assignee:
Pfizer Inc., New York, NY (US);
Primary Examiner:
Int. Cl.
CPC ...
C07D / ; C07D / ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
514210 ; 540203 ; 548241 ; 548242 ; 548408 ; 548410 ; 549330 ; 549345 ; 549405 ; 560 31 ; 560 35 ; 560 39 ; 560 51 ; 560 53 ; 560 54 ; 560315 ; 562435 ; 562462 ; 564265 ;
Abstract
Certain spirocyclic heterocyclic compounds, and their pharmaceutically-acceptable salts, are inhibitors of the aldose reductase enzyme, and so are useful for the control of diabetic complications. Exemplary compounds include compounds of the formula ##STR1## wherein Y is ##STR2## X is --O-- or ##STR3## R.sub.1 and R.sub.2 are each independently H, alkyl C.sub.1 -C.sub.6,aryl or arylalkyl (C.sub.1 -C.sub.6);