The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 23, 1991
Filed:
Oct. 16, 1990
Applicant:
Inventors:
James L Gaylor, Skillman, NJ (US);
Paul R Johnson, Newark, DE (US);
Soo S Ko, Wilmington, DE (US);
Ronald L Magolda, Aston, PA (US);
Simon H Stam, San Jose, CA (US);
James M Trzaskos, Boothwyn, PA (US);
Assignee:
E. I. Du Pont de Nemours and Company, Wilmington, DE (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07J / ;
U.S. Cl.
CPC ...
552540 ; 552515 ; 552516 ; 552519 ; 552523 ; 552537 ; 552526 ; 552540 ; 552544 ; 540 94 ; 540120 ;
Abstract
Lanosterols substituted in the 14 and/or 15 position(s) which are active in inhibiting lanosta-8,24-dien-3.beta.-ol 14.alpha.-methyl-demethylase activity, suppressing 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGR) activity, decreasing cholesterol synthesis and reducing serum cholesterol levels are disclosed.