The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 23, 1991
Filed:
Aug. 27, 1990
Applicant:
Inventor:
Fred G Schreiber, Highland Park, NJ (US);
Assignee:
Biocraft Laboratories, Inc., Fairlawn, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D / ;
U.S. Cl.
CPC ...
540230 ; 540215 ;
Abstract
A method for obtaining improved cophalexin monohydrate or cephradine monohydrate yields and purities in the syntheses of such materials by the acylation of silyl esters of 7-ADCA, which involves admixing a cephalexin or cephradine-containing system with base to separate the acid acceptor employed during acylation from the product, and thereafter separating the aqueous phase containing the cephalosporin anion from the organin phase containing the acid acceptor, to thereby prevent contamination of the desired product by the acid acceptor.