The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 09, 1991
Filed:
Apr. 01, 1986
Applicant:
Inventors:
Garth L Nicolson, Kingwood, TX (US);
Susan M North, Houston, TX (US);
Peter A Steck, Houston, TX (US);
Assignee:
Board of Regents, The University of Texas System, Austin, TX (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N / ; G01N / ; C07K / ; C07K / ;
U.S. Cl.
CPC ...
435-723 ; 424 858 ; 435 693 ; 4351722 ; 43524027 ; 435975 ; 436501 ; 436503 ; 436536 ; 436543 ; 436547 ; 436548 ; 436 64 ; 436808 ; 436813 ; 530387 ; 530395 ; 530403 ; 530413 ; 530417 ; 530828 ; 935107 ; 935110 ;
Abstract
Disclosed are monoclonal antibodies which react with human tumor cells, particularly metastatic human tumor cells, but not with normal human tissues tested. The monoclonal antibodies are prepared against a 580 kilodalton glycoprotein antigen, designated gp580, which is isolated from either rat or human tumor cells. Methods for isolating the glycoprotein antigen are disclosed as well. Moreover, techniques are disclosed for utilizing these antibodies both in the detection and in the prevention of human tumor lesions.