The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 09, 1991
Filed:
Oct. 12, 1984
Robert P Lenk, Lambertville, NJ (US);
Michael W Fountain, Griggstown, NJ (US);
Andrew S Janoff, Yardley, PA (US);
Mircea C Popescu, Plainsboro, NJ (US);
Steven J Weiss, Hightstown, NJ (US);
Richard S Ginsberg, Monroe Township,, NJ (US);
Marc J Ostro, Griggstown, NJ (US);
Sol M Gruner, Lawrenceville, NJ (US);
The Liposome Company, Inc., Princeton, NJ (US);
Abstract
A new and substantially improved type of lipid vesicle, called stable plurilamellar vesicles (SPLVs), are described, as well as the process for making the same and X-ray diffraction methods for identifying the same. SPLVs are characterized by lipid bilayers enclosing aqueous compartments containing one or more entrapped solutes, the concentration of such solutes in each aqueous compartment being substantially equal to the concentration of solutes used to prepare the SPLVs. The bilayers of SPLVs are substantially non-compressed. SPLVs are stable during storage and can be used in vivo for the sustained release of compounds and in the treatment of disease.