The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 02, 1991
Filed:
Oct. 28, 1988
Anthony R Torres, Logan, UT (US);
Elbert A Peterson, Garrett Park, MD (US);
Other;
Abstract
A method of separating charged molecules having different numbers of charges thereon includes the step of passing the molecules to be separated through ion-exchange material such as an ion-exchange chromatograpy column in normal manner so that molecules to be separated bind to the ion-exchange material. Displacer molecules are then passed through the ion-exchange column to selectively release certain of the molecules to be separated from the ion-exchange material, while others of the molecules to be separated remain bound to the material. Rather than the displacer molecules having charges of a similar sign to the molecules to be separated so that the displacer molecules bind to the ion-exchange material in place of certain of the molecules to be separated thereby releasing them, the displacer molecules have charges of the same sign as the ion-exchange material and opposite the sign of the molecules to be separated so that certain of the molecules to be separated bind to the displacer molecules in place of the ion-exchange material and are thus released from the ion-exchange material and flow from the ion-exchange material with the diplacers. Displacers of various numbers of charges may be sequentially passed through the ion-exchange material in ascending number of charge order to thereby selectively release molecules to be separated. The last remaining molecules to be separated may be released selectively with displacer molecules or, may be released in known manner such as by elution.