The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 02, 1991

Filed:

Jul. 13, 1989
Applicant:
Inventors:

William D Fuller, San Diego, CA (US);

Michael P Cohen, Salona Beach, CA (US);

Fred R Naider, Staten Island, NY (US);

Murray Goodman, LaJolla, CA (US);

Assignee:

Bioresearch, Inc., Farmingdale, NY (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K / ; C07D / ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
530335 ; 530333 ; 530334 ; 530337 ; 548227 ; 548183 ; 548188 ; 544 97 ; 544 54 ; 540488 ;
Abstract

Urethane-protected NCAs and MTAs are prepared by reacting an NCA or NTA with a haloformate in an inert diluent, under anhydrous conditions and in the presence of a tertiary nitrogen-containing base having an atom or functional group sufficiently electron rich and positioned relative to the nitrogen of said base so as to render said atom or group capable of complexing with the H--N< group of said N-carboxyanhydride or N-thiocarboxyanhydride but able to generate N-carboxyanhydride or N-thiocarboxyanhydride anionic complexes capable of reacting with the haloformate.


Find Patent Forward Citations

Loading…