The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 25, 1991
Filed:
Apr. 06, 1989
Applicant:
Inventors:
Peter E Daddona, West Chester, PA (US);
Harvey J Berger, Devon, PA (US);
Rodger P McEver, Oklahoma City, OK (US);
Assignee:
Centocor, Inc., Malvern, PA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ;
U.S. Cl.
CPC ...
424-11 ; 424 8591 ;
Abstract
This invention pertains to a method of imaging atherosclerotic plaque using radiolabeled monoclonal antibodies that are specific for activated platelets or activated endothelial cells. The method is capable of determining the site of endothelial injury. This method involves the administration of a platelet-specific labeled monoclonal antibody or antibody fragment to a patient. The antibody is allowed to accumulate at the plaque site and the plaque is then scanned with a photoscanner. The detected signals are then converted into an image of the plaque.