The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 11, 1991
Filed:
Aug. 13, 1987
Hans Reichenbach, Wolfenbuttel, DE;
Klaus Gerth, Braunschweig, DE;
Herbert Irschik, Wolfenbuttel, DE;
Brigitte Kunze, Braunschweig, DE;
Gerhard Hofle, Braunschweig, DE;
Hermann Augustiniak, Wolfenbuttel, DE;
Norbert Bedorf, Konigslutter, DE;
Rolf Jansen, Braunschweig, DE;
Wolfram Trowitzsch-Kienast, Braunschweig, DE;
Heinrich Steinmetz, Hildesheim-Sorsum, DE;
Ciba-Geigy Corporation, Ardsley, NY (US);
Gesellschaft fur Biotechnologische Forschung mbH, Braunschweig, DE;
Abstract
The invention relates to novel polycyclic alkaloids of formula ##STR1## in which R.sup.1 represents hydrogen or hydroxy, R.sup.2 represents hydrogen or acyl and A and B, independently of one another, each represents C.dbd.O or C--OH, and wherein the dashed line represents a C.dbd.C double bond at the position of the middle bond when A or B represents C.dbd.O, or at the position of the two outer bonds when A or B represents C--OH, a process for the manufacture of these compounds by fermentation of a novel microorganism of the species Myxococcus xanthus, the novel microorganism itself, pharmacetical preparations that contain the novel compounds, and the use of the novel compounds as antibiotics and as tumour-inhibiting agents and for the manufacture of pharmaceutical preparations.