The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 21, 1991

Filed:

Feb. 23, 1988
Applicant:
Inventors:

Robert N Young, Senneville, CA;

Joshua Rokach, Chomedy, CA;

Haydn R Williams, Dollard Des Ormeaux, CA;

Masatoshi Kakushima, Quebec, CA;

Yvan Guindon, Ile Bizard, CA;

Assignee:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; C07D / ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
514312 ; 514311 ; 514313 ; 514314 ; 544336 ; 544405 ; 544408 ; 544409 ; 548252 ; 548469 ; 548494 ; 548495 ; 548503 ; 548517 ; 548518 ; 548528 ; 548541 ; 548543 ; 549402 ; 549416 ; 549417 ; 549420 ; 549214 ; 549423 ; 549468 ; 549561 ; 560-9 ; 560 10 ; 560 15 ; 560 16 ; 560 17 ; 560 18 ; 560 22 ; 560 53 ; 560 55 ; 560 60 ; 562426 ; 562427 ; 562431 ; 562581 ; 564440 ; 568813 ; 570182 ; 570185 ; 546153 ; 546154 ; 546155 ; 546156 ; 546157 ; 546159 ; 546162 ; 546168 ; 546169 ; 546170 ; 546172 ; 546173 ; 546174 ; 546175 ; 546176 ; 546178 ; 546268 ; 546329 ; 546330 ; 546339 ; 546340 ; 546341 ; 546342 ;
Abstract

Compounds of the Formula I: ##STR1## and pharmaceutically acceptable salts thereof are leukotriene antagonists. These compounds inhibit SRS-A and leukotriene synthesis and are antagonists of SRS-A and are thus useful in the treatment of asthma, allergic disorders, inflammation, skin diseases and certain cardiovascular disorders.


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