The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 07, 1991
Filed:
Oct. 02, 1989
Glaxo Group Limited, , GB;
Abstract
Compounds of formula ##STR1## wherein R.sup.1 or R.sup.2 represents a C.sub.1-6 alkyl group optionally substituted by one to three halogen atoms and the other represents a phenyl or pyridyl ring or N-oxide thereof optionally substituted by one or more substituents selected from halogen atoms and hydroxyl, C.sub.1-3 alkyl, C.sub.1-3 alkoxy and trifluoromethyl groups; wherein R.sup.3 represents a phenyl or pyridyl ring or N-oxide thereof optionally substituted by one or more substituents selected from halogen atoms and hydroxyl, C.sub.1-3 alkyl, C.sub.1-3 alkoxy and trifluoromethyl groups with the proviso that only one of the groups R.sup.1, R.sup.2 or R.sup.3 represents an optionally substituted pyridyl ring; X represents --CH.dbd.CH--; and Z represents ##STR2## wherein R.sup.4 represents a hydrogen atom, a carboxyl protecting group or a cation; and R.sup.5 represents a hydrogen atom or a C.sub.1-3 alkyl group; a solvate thereof, or acid addition salts of compounds wherein R.sup.4 represents a hydrogen atom or a carboxyl protecting group; for use in the treatment and/or prevention of diseases associated with hypercholesteroloma and hyperlipoproteinemia.