The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 07, 1991
Filed:
Mar. 15, 1988
Applicant:
Inventors:
Alessandro Sisto, Rome, IT;
Antonio Verdini, Monterotondo, IT;
Assignees:
Eniricerche S.p.A., Milan, IT;
Sclavo S.p.A., Siena, IT;
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C07C / ; C07C / ;
U.S. Cl.
CPC ...
514 19 ; 514 18 ; 530330 ; 530331 ; 560169 ; 562560 ;
Abstract
New retro-inverso analogs of thymopentin (TP5) and of its tripeptide fragment (TP5.sup.1-3) of general formula (I) ##STR1## are described wherein R is hydrogen or an acyl radical, and R.sup.1 is --OR.sup.2 or ##STR2## wherein R.sup.2 is hydrogen or a hydrocarbyl radical, and the corresponding pharmaceutically acceptable acid- or base-addition salts. The new compounds are enzyme-resistant immunomodulatory peptides.