The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 07, 1991

Filed:

Oct. 20, 1989
Applicant:
Inventors:

Martin C Woodle, Menlo Park, CA (US);

Francis J Martin, San Francisco, CA (US);

Annie Yau-Young, Los Altos, CA (US);

Carl T Redemann, Walnut Creek, CA (US);

Assignee:

Liposome Technology, Inc., Menlo Park, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ;
U.S. Cl.
CPC ...
424450 ; 424-11 ; 264-43 ;
Abstract

A liposome composition which contains between 1-20 mole percent of an amphipathic lipid derivatized with a polyalkylether, as exemplified by phosphatidylethanolamine derivatized with polyethyleneglycol. The derivatized lipid enchances the circulation time of the liposomes severalfold, and this enhancement is achieved with either fluid or membrane-rigidifying liposome components. Also disclosed are methods for delivering a drug for slow release from the bloodstream, and for targeting a selected tissue or cells with liposomes, via the bloodstream.

Published as:
CA2067133A1; CA2067178A1; WO9105545A1; WO9105546A1; US5013556A; AU6637490A; AU6898291A; NO921214D0; NO921213D0; FI921764L; FI921763A7; FI921763L; NO921214L; NO921213L; EP0496813A1; EP0496835A1; KR920703012A; KR920703013A; JPH05501264A; US5213804A; JPH05505173A; AU642679B2; AU654120B2; EP0496813B1; ATE115401T1; DE69015207D1; IL96070A; DE69015207T2; EP0496835B1; ATE122229T1; DE69019366D1; ES2071976T3; DK0496835T3; DE69019366T2; GR3017060T3; IL96069A; HK14097A; NL960031I1; LU88854I2; CA2067178C; JP2667051B2; JPH101431A; KR0134982B1; CA2067133C; NO304637B1; NO1999003I1; JP2889549B2; FI105151B; JP2001181214A; JP3571335B2; NL960031I2; JP3921050B2; DE19675048I2;

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