The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 07, 1991
Filed:
Dec. 04, 1989
Thomas J Bellos, St. Louis, MO (US);
Richard D Keating, Bridgeton, MO (US);
Petrolite Corporation, St. Louis, MO (US);
Abstract
A method for resolving emulsions produced in preparation of pharmaceuticals by fermentation and in other such bioprocesses is disclosed. The method comprises adding an effective amount of a demulsifier to an emulsion containing fermentation product that includes a pharmaceutical which is desired to be extracted from the emulsion. The demulsifier comprises a nitrogen composition that is selected from among certain quaternized and unquaternized polyoxyalkylated amines, their conjugate acid salts, quaternized and unquaternized condensation product formed by heating an oxyalkylated amine under dehydration condensation conditions to product a polyoxyalkylated amine of molecular weight of at least 400, conjugate acid salts thereof, quaternized and unquaternized copolymers of an epihalohydrin and an amine selected from the group consisting of lower aliphatic primary amines having from two to about eight carbon atoms and lower aliphatic secondary amines having from two to about eight carbon atoms, polydialkyldiallyl ammonium salts, polymers of acrolamido alkylene quaternary ammonium salts, and mixtures thereof.