The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 16, 1991
Filed:
Jun. 18, 1990
John C Mazziotta, Beverly Hills, CA (US);
Farhad Daghighian, New York, NY (US);
Edward J Hoffman, Van Nuys, CA (US);
The Regents of the University of California, Oakland, CA (US);
Abstract
An intraoperative radiation probe is devised to detect radiolabelled malignant tissues by being selectively sensitive to beta radiation while insensitive to gamma radiation. The probe is comprised of two plastic scintillators optically coupled to corresponding photomultiplier tubes via corresponding light pipes. One of the plastic scintillators is shielded against beta radiation while the other is left to detect both beta and gamma radiation. The gamma radiation sensitivity of the dual probes is empirically established and used as a weighted factor to subtract the outputs of the two probes to leave a signal indicative of the beta radiation emitted by the radiolabelled tissue. Because of the shorter range of beta radiation within tissue, only near radiolabelled tissue is detected by the probe while strongly radiolabelled, more distant tissues exposing the probe to gamma radiation are ignored. The reliably identified near radiolabelled tissues can then be surgically removed. The probe is usable in any application where local beta radiation is to be differentiated from other types and sources of radiation.