The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 02, 1991
Filed:
Sep. 24, 1986
Applicant:
Inventors:
James M Frincke, Olivenhain, CA (US);
Richard M Bartholomew, San Diego, CA (US);
Robert O Dillman, Solana Beach, CA (US);
Assignee:
Hybritech Incorporated, San Diego, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ;
U.S. Cl.
CPC ...
424 858 ; 424 8591 ; 424 86 ; 424 87 ; 424 88 ; 530387 ; 530388 ; 530389 ; 514-2 ; 514885 ;
Abstract
A composition comprising a non-covalent immunocomplex of an anthracycline agent and an antibody selected to bind a target antigen and enhance the cytotoxicity of the anthracycline agent is disclosed. In accordance with the invention, the efficacy of an anthracycline as an anti-tumor agent for use in in vivo therapy is enhanced by administering to a patient a non-covalent immunocomplex provided herein.