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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 5002869 B1

PDFFull Text
Date of Patent:
Mar. 26, 1991

Filed:

Nov. 02, 1987

Monoclonal antibody specific to a novel epitope of the lfa-1 antigen of

Applicant:
Inventors:

Stuart F Schlossman, Newton Center, MA (US);

Chikao Morimoto, Needham, MA (US);

Assignee:

Dana-Farber Cancer Institute, Boston, MA (US);

Attorney:

Cass; Myron C.

Primary Examiner:

Esther L Kepplinger

Assistant Examiner:

David A Saunders

Int. Cl.
CPC ...
A61K / ; G01N / ; G01N / ; C12N / ;
U.S. Cl.
CPC ...
435-724 ; 424-11 ; 424 8591 ; 424 34 ; 4241722 ; 42424027 ; 424948 ; 436503 ; 436548 ; 530387 ; 530391 ; 530809 ; 935104 ; 935110 ;
Abstract

A monoclonal antibody which binds preferentially to a subset of the human CD8 lymphocyte population whereby to positively and precisely distinguish between cytotoxic effector and supressor effector cells in the CD8 cell population. The monoclonal antibody recognizes a novel epitope of LFA-1 antigen by means of which it can bind CD8 cells which express the eptope on a surface antigen thereof. The CD8 subset cell population to which this anitbody binds preferentially is the CD8 cytotoxic effector population. This selectivity of the monoclonal antibody enables cell sorting, diagnostic and positive therapeutic applications thereof to be utilized.

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Schlossman, Stuart. (1991). Monoclonal antibody specific to a novel epitope of the lfa-1 antigen of (U.S. Patent No. 5002869). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/5002869

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