The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 19, 1991

Filed:

Jul. 23, 1990
Applicant:
Inventors:

Francis E Gould, Princeton, NJ (US);

Christian W Johnston, Neshanic Station, NJ (US);

George E Seems, Pennington, NJ (US);

Assignee:

Tyndale Plains-Hunter Ltd., Princeton, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C08J / ; C08L / ; C12N / ;
U.S. Cl.
CPC ...
424409 ; 424 60 ; 424 63 ; 424 65 ; 424 69 ; 424422 ; 424486 ; 424 78 ; 514863 ; 522105 ; 524591 ; 524916 ; 435182 ;
Abstract

Thermally reversible polyurethane hydrogels are formed by adding water to a gel forming hydrophilic polyurethane polymer produced by reacting under anhydrous conditions a non-aromatic organic diisocyanate with a glycol component in an NCO/OH mole weight ratio of from about 0.900/1 to about 0.980/1, the glycol component having a number average molecular weight of from about 1000 to 3500 wherein the percentage by weight of the diisocyanate in the reaction mixture is from about 7% to about 20%. The hydrogels are solids at room temperature but liquify at higher temperatures such as body temperature and therefore are useful as carriers for the protection, delivery and sustained release of a variety of active agents including pharmaceuticals, cosmetics, living cells and organisms.


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