The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 26, 1991
Filed:
Oct. 12, 1989
Reijo J Toivola, Oulu, FI;
Arto J Karjalainen, Oulu, FI;
Kauko O Kurkela, Oulu, FI;
Marja-Liisa Soderwall, Oulu, FI;
Lauri V Kangas, Turku, FI;
Guillermo L Blanco, Oulu, FI;
Hannu K Sundquist, Kaarina, FI;
Farmos Group Ltd., Turku, FI;
Abstract
##STR1## wherein n is 0 to 4, R.sub.1 and R.sub.2, which can be the same or different, are H or OH; R.sub.3 is --O--(CH.sub.2).sub.m --CH.sub.2 --NR.sub.6 R.sub.7 wherein m is 1 or 2, R.sub.6 and R.sub.7, which can be the same or different, are H or an alkyl group of 1 to 4 carbon atoms, or --NR.sub.6 R.sub.7 can form a pyrrolidinyl group; and R.sub.4 is halogen, and their non-toxic pharmaceutically acceptable salts and phenolic esters of aliphatic or aromatic carboxylic acids, acid anhydrides or acid chlorides thereof are disclosed. These compounds exhibit valuable pharmacological properties as estrogenic, anti-estrogenic, and progestanic agents. They show activity against oestrogen-dependent tumors.