The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 19, 1991

Filed:

Jun. 17, 1988
Applicant:
Inventors:

Elliot M Levine, Cherry Hill, NJ (US);

Sandor S Shapiro, Philadelphia, PA (US);

Bruce E Jarrell, Philadelphia, PA (US);

Assignees:

The Wistar Institute, Philadelphia, PA (US);

The Thomas Jefferson University, Philadelphia, PA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N / ; C12N / ; C12N / ;
U.S. Cl.
CPC ...
4352402 ; 435-1 ; 43524023 ; 435948 ;
Abstract

Vigorous growth of endothelial cells from human umbilical vein endothelial cells in vitro is achieved using a culture medium containing endothelial cell growth factor and heparin and/or dextran sulfate. Cell population doubling times of 13 to 21 hours for 60 to 85 populations doublings are obtained, and cloned human endothelial cell strains are established having similar proliferative capacities.


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