The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 05, 1991

Filed:

Jan. 24, 1989
Applicant:
Inventors:

Erasmus Huber, Garching, DE;

Christian Klein, Weilheim, DE;

Gunter Pappert, Tutzing, DE;

Klaus Hallermayer, Munich, DE;

Assignee:

Boehringer Mannheim GmbH, Mannheim, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q / ; G01N / ;
U.S. Cl.
CPC ...
435-79 ; 435 14 ; 435 28 ; 435-792 ; 435961 ; 436543 ; 530350 ; 530402 ; 530403 ; 530405 ;
Abstract

The present invention provides hapten derivatives of the general formula: ##STR1## wherein Hap is a residue formed from a hapten carrying a keto or aldehyde group by splitting off an oxo group and R.sup.1 and R.sup.2, which can be the same or different, are alkyl radicals containing up to 7 carbon atoms and one of the symbols R.sup.1 and R.sup.2 can also represent a hydrogen atom. The present invention also provides hapten-protein conjugates of the general formula: ##STR2## wherein Hap, R.sup.1 and R.sup.2 have the above-given meanings and E--NH is the residue of a protein bound via an .epsilon.-amino group of a lysine residue.


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