The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 29, 1991

Filed:

Dec. 21, 1989
Applicant:
Inventors:

Jean-Francois Gourvest, Joinville Le Pont, FR;

Dominique Lesuisse, Paris, FR;

Daniel Philibert, La Varenne Saint Hilaire, FR;

Jean P Vevert, Pantin, FR;

Assignee:

Roussel Uclaf, Paris, FR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; C07J / ; C07J / ;
U.S. Cl.
CPC ...
514177 ; 514178 ; 514179 ; 552511 ; 552515 ; 552523 ;
Abstract

A compound of the formula ##STR1## wherein R is selected from the group consisting of alkyl of 1 to 4 carbon atoms and alkenyl and alkynyl of 2 to 4 carbon atoms, R.sub.1 is alkyl of 1 to 6 carbon atoms unsubstituted or substituted with at least one member of the group consisting of alkoxy and alkylthio of 1 to 4 carbon atoms, --NO.sub.2, --CN and halogen, X and Y together are .dbd.O or Y is hydrogen and X is --OH, etherified --OH or esterified --OH, the dotted lines in the 1(2), 6(7) and 9(11) positions indicate a possible double bond with the proviso that R.sub.1 is alkyl of 1 to 6 carbon atoms when X and Y are .dbd.O and there is a double bond in at least one of the 1(2), 6(7) and 9(11) positions having aromatase inhibiting activity.


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