The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 15, 1991
Filed:
Dec. 07, 1988
Applicant:
Inventors:
Derk Hamminga, Weesp, NL;
Hans H Haeck, Weesp, NL;
Ineke Van Wijngaarden, Weesp, NL;
Wouter Wouters, Weesp, NL;
Assignee:
Duphar International Research B.V., Weesp, NL;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
514211 ; 514214 ; 514217 ; 514220 ; 514304 ; 514305 ; 540468 ; 540472 ; 540479 ; 540558 ; 540586 ; 540544 ; 540546 ;
Abstract
The invention relates to new 1,7-annelated esters and amides of indolecarboxylic acids having general formula 2, ##STR1## wherein the symbols have the meanings given in the specification. The compounds and their salts are very strong and selective antagonists of 'neuronal' 5-hydroxytryptamine (5-HT) receptors, and can be used for the treatment of symptoms which are caused by over-stimulation of these receptors.