The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 15, 1991
Filed:
Sep. 17, 1987
Applicant:
Inventors:
Mitsuyoshi Morii, Yokohama, JP;
Masaharu Ohoka, Yokohama, JP;
Toshihiko Suzuki, Tokyo, JP;
Katsuyuki Suzuki, Hiroshima, JP;
Nobuhiro Kawashima, Sagamihara, JP;
Noriko Morii, Yokohama, JP;
Kunizou Mori, Yokohama, JP;
Assignee:
Mitsui Toatsu Chemicals Incorporated, Tokyo, JP;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N / ; C12N / ;
U.S. Cl.
CPC ...
435226 ; 435212 ; 435219 ; 435815 ;
Abstract
Tissue plasminogen activator (tPA) species having a molecular weight of about 70,000 daltons is isolated in a purified form from a crude tPA preparation containing various tPA species having different molecular weights by bringing the crude tPA preparation into contact with a cation exchanger in advance and separating the desired tPA species selectively from the cation exchanger by means of the salt gradient elution method.