The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 15, 1991

Filed:

Sep. 29, 1988
Applicant:
Inventors:

David J Bowman, Manchester, GB;

Raymond F Cosgrove, Wallasey, GB;

Terence P Male, Helsby, GB;

Robert Evans, Liverpool, GB;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
B01L / ; B05C / ; G01N / ;
U.S. Cl.
CPC ...
422 99 ; 422102 ; 422104 ; 422 58 ; 435292 ; 435299 ; 350536 ; 356244 ; 118500 ;
Abstract

A tissue or like processing method involving application of liquids to carrier-mounted material, e.g. a thin tissue section mounted on a microscope slide (10), is characterized by disposing a channel-defining element (1) adjacent to the carrier (10) to form an assembly providing an enclosure (11) for the material on the carrier. The enclosure (11) has an inlet (13) and an outlet (14) and has capillary dimensions. The assembly is disposed with the inlet (13) above the outlet (14) and liquid introduced into the inlet fills the enclosure and is retained in contact with the material on the carrier by surface tension effect. Further liquid introduced to the inlet (13) displaces the first liquid progressively to the outlet (14). A sequence of liquids can thus be brought successively into contact with the material with minimum wastage, by feeding the liquids successively to the inlet (13) of an assembly. A support for a plurality of assemblies to permit concurrent operations upon a set of material samples is disclosed, and a machine for automated processing, e.g. immunostaining, of a batch of tissue samples is also disclosed.


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