The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 01, 1991
Filed:
Jun. 26, 1986
Applicant:
Inventor:
Daniel B Wagner, Raleigh, NC (US);
Assignee:
Becton, Dickinson and Company, Franklin Lakes, NJ (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12M / ;
U.S. Cl.
CPC ...
435288 ; 128637 ; 128665 ; 356 39 ; 356445 ; 422 58 ; 422 8209 ; 422 8208 ; 435 14 ; 435 25 ; 435310 ; 436 95 ; 436136 ; 436138 ; 436800 ; 436805 ; 436904 ;
Abstract
A method for monitoring the glucose level in a body fluid uses an apparatus which includes a conjugate of glucose oxidase with a fluorescent dye coated onto an optical fiber in contact with the body fluid, a source of excitation light and a fluorescence emission detector. Glucose is oxidized by oxygen in the body fluid causing a decrease in oxygen concentration at the enzyme. The fluorescent dye is sensitive to oxygen quenching so that, when the oxygen concentration decreases, fluorescence emission increases in direct proportion to the glucose concentration in the fluid.