The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 18, 1990
Filed:
Jul. 02, 1986
Applicant:
Inventors:
Patrick Jouin, Amiane, FR;
Dino Nisato, Saint Georges D'Orques, FR;
Bertrand Castro, Saint Aunes, FR;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D / ; C07D / ; C07C / ; C07C / ;
U.S. Cl.
CPC ...
548497 ; 548344 ; 548543 ; 548538 ; 548498 ; 560 29 ; 560 39 ; 560115 ; 560148 ; 560153 ; 560158 ; 560159 ; 560169 ; 560170 ; 560179 ; 560125 ; 562444 ; 562507 ; 562567 ; 562556 ; 562561 ; 260404 ; 2604109 ; 549274 ; 549333 ; 549372 ;
Abstract
The process described makes it possible to obtain optically pure 4-amino-3-hydroxycarboxylic acids by means of a series of stereoselective steps. The starting material is an alpha-amino acid in the L or D configuration, with which Meldrum's acid is reacted. The resulting pyrrolone derivative is reduced prior to opening of the pyrrolidine ring. The invention also relates to the new products obtained by the said process and to the pyrrolone derivatives obtained as intermediates.