The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 11, 1990

Filed:

Jan. 14, 1987
Applicant:
Inventors:

William J Louis, Rosanna, Victoria, 3084, AU;

Richard Berthold, Bottringen, CH;

Max-Peter Seiler, Riehen, CH;

Andre Stoll, Birsfelden, CH;

Assignee:

Other;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C09D / ; C07C / ; C07C / ; C07C / ; C07C / ; C07C / ; A61K / ; A61K / ; A61K / ;
U.S. Cl.
CPC ...
5142375 ; 5142378 ; 514259 ; 514260 ; 514261 ; 514383 ; 514393 ; 514395 ; 514398 ; 514403 ; 514404 ; 514405 ; 514415 ; 514416 ; 514418 ; 514419 ; 514427 ; 514438 ; 514447 ; 514448 ; 514459 ; 514471 ; 514472 ; 544134 ; 544319 ; 544336 ; 546153 ; 546323 ; 548371 ; 564 47 ; 564 56 ; 564182 ; 564186 ;
Abstract

Compounds of formula (I), ##STR1## characterized in that R signifies optionally substituted heteroaryl-, heteroarylakyl or heteroarylalkenyl, R.sub.1 signifies hydrogen or a substituent, R.sub.2 is hydroxy or a group --z--(CH.sub.2).sub.n --Y--R.sub.3 wherein R.sub.3 is hydrogen, alkyl, hydroxyalkyl, alkenyl, cycloalkyl, cycloalkylalkylene, hydroxy substituted cycloalkyl or cycloalkylalkylene, or optionally substituted aryl or aralkyl or aralkenyl moiety, and Y signifies oxygen or sulfur, and either Z is an oxygen atom and n is 2 or 3, or Z is a bond and n is 1, 2 or 3, A signifies alkylene or branched alkylene of 2 to 5 carbon atoms, W signifies a bond or imino, and X signifies a bond or imino, and their physiologically hydrolyzable derivatives, in which at least one hydroxy group is in esterified form. The compounds exhibit beta adrenoceptor blocking activity. Processes for the preparation of the compounds are also disclosed.


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