The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 04, 1990
Filed:
Dec. 24, 1987
Applicant:
Inventors:
Gerald L Rowley, San Jose, CA (US);
Larry R Hillis, Milpitas, CA (US);
Assignee:
Sclavo, Inc., Sunnyvale, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C08B / ;
U.S. Cl.
CPC ...
536 51 ; 536112 ; 436529 ; 514 59 ;
Abstract
A method to convert the hydroxyl groups of solubilized dextran to the tresylate forms which can be displaced by a nucleophile is disclosed. The method of the invention requires the reaction of dextran with the tresylating reagent in the presence of dry DMSO. The resulting tresylate can be converted to labeled dextrans which have direct linkages of a nucleophilic label to the carbons of the dextran backbone.