The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 27, 1990
Filed:
Mar. 17, 1989
Peter K Chiang, Bethesda, MD (US);
Haim Leader, Ramat Hasharm, IL;
Ruthann M Smeikal, Silver Spring, MD (US);
Richard K Gordon, Rockville, MD (US);
Charlotte S Payne, Washington, DC (US);
Bhupendra P Doctor, Potomac, MD (US);
Felipe N Padilla, Wheaton, MD (US);
The United States of America as represented by the Secretary of the Army, Washington, DC (US);
Abstract
Novel carbaphens are provided of the formula ##STR1## wherein R is OH, OCON(CH.sub.3).sub.2 or OCONHCH.sub.3, and R' is H, OH or .sub.2 OCON(CH.sub.3).sub.2, stereoisomers thereof, pharmaceutically-acceptable salts thereof or mixtures thereof. Compositions comprise the carbaphens with pharmaceutically acceptable carriers, and they may further comprise other drugs as well. Methods of treating patients either prophylactically or therapeutically which suffer from organophosphate poisoning, coronary insufficiency, cerebral vasospasms, spastic cholitis and cholecystitis comprise the administration of the carbaphens of the invention.