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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 4973578 B1

PDFFull Text
Date of Patent:
Nov. 27, 1990

Filed:

Mar. 17, 1988

Synthetic peptides derived from the alpha-subunit of human lycoprotein

Applicant:
Inventors:

Robert J Ryan, Rochester, MN (US);

Daniel J McCormick, Rochester, MN (US);

John C Morris, Rochester, MN (US);

M Cristine Charlesworth, Rochester, MN (US);

Assignee:

Mayo Foundation for Medical Education and Research, Rochester, MN (US);

Attorney:

Merchant, Gould, Smith, Edell, Welter & Schmidt, P.A.

Primary Examiner:

F T Moezie

Int. Cl.
CPC ...
C07K / ; C07K / ; A61K / ; A61K / ;
U.S. Cl.
CPC ...
514 12 ; 514 13 ; 514 14 ; 514-8 ; 530325 ; 530326 ; 530324 ; 530395 ; 530397 ; 530850 ; 530854 ;
Abstract

Synthetic peptides corresponding to .alpha.-subunit of human glycoprotein hormone amino acid regions .alpha.31-45, .alpha.21-35, .alpha.26-46 and .alpha.81-92; were found to inhibit binding of 125.sub.I-bTSH to human thyroid. Peptides corresponding to regions .alpha.26-46 and .alpha.31-45 were also found to potently inhibit the stimulation of adenylate cyclase activity by bTSH in a TSH bioassay using FRTL-5 cells and block the action of thyroid stimulating immunoglobulin.

Find Patent Forward Citations

Ryan, Robert. (1990). Synthetic peptides derived from the alpha-subunit of human lycoprotein (U.S. Patent No. 4973578). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/4973578

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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