The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 20, 1990

Filed:

Jan. 24, 1989
Applicant:
Inventors:

Yasuo Itoh, Katsuyamashi, JP;

Hideo Kato, Fukuishi, JP;

Eiichi Koshinaka, Katsuyamashi, JP;

Nobuo Ogawa, Katsuyamashi, JP;

Kazuya Mitani, Fukuishi, JP;

Shunichiro Sakurai, Katsuyamashi, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C / ; C07C / ; A61K / ; A61K / ; C07D / ;
U.S. Cl.
CPC ...
514408 ; 514601 ; 514602 ; 514603 ; 548542 ; 564 84 ; 564 86 ; 564 90 ;
Abstract

Phenoxyethylamine derivatives represented by the general formula (I): ##STR1## wherein R.sub.1 and R.sub.5 represent lower-alkyl, R.sub.2 and R.sub.3, which may be the same or different, each represents hydrogen or lower-alkyl, or ##STR2## represents a 5- or 6-membered ring system which may include nitrogen, oxygen or sulfur as a ring membered atom, R.sub.4 represents hydrogen or lower-alkyl, and n represents an integer selected from 1 to 3, their optical isomers and pharmacologically-acceptable acid addition salts, which exhibit excellent .alpha..sub.1 -blocking activity, a process for their preparation, pharmaceutical compositions thereof, and a method for the treatment of a subject afflicted with hypertension or dysuria by administrating such a compound, are all disclosed.


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