The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 13, 1990
Filed:
Sep. 28, 1989
Tsuneo Okonogi, Yokohama, JP;
Yasushi Murai, Yokohama, JP;
Masahiro Onodera, Yokohama, JP;
Toshio Nishizuka, Yokohama, JP;
Yasuhiko Abat, Yokohama, JP;
Seiji Shibahara, Yokohama, JP;
Shigeharu Inouye, Yokohama, JP;
Meiji Seika Kaisha, Ltd., Tokyo, JP;
Abstract
The crystalline dihydrochloride of a specific cephalosporin derivative is stable to heat and retains its antibacterial activity even after storage over long periods at high temperature. The crystalline dihydrochloride can be obtained by removing protective groups from the cephalosporin derivative wherein the amino group and carboxy groups are protected and then crystallizing the cephalosporin derivative from a hydrochloric acid aqueous solution. The crystalline dihydrochloride is useful for pharmaceutical preparations.