The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 30, 1990
Filed:
Jul. 31, 1985
Applicant:
Inventors:
Francis P McCormick, Albany, CA (US);
Michael A Innis, Oakland, CA (US);
Gordon M Ringold, Palo Alto, CA (US);
Assignee:
Cetus Corporation, Emeryville, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12P / ; C12N / ; C12N / ; C07H / ;
U.S. Cl.
CPC ...
435 6951 ; 435 701 ; 435 703 ; 435 705 ; 4351721 ; 4351723 ; 4352402 ; 435320 ; 435811 ; 536 27 ; 935 11 ; 935 34 ; 935 70 ;
Abstract
DNA constructs are prepared which operably link human interferon genes, selective, eukaryotic marker genes, and promoter and expression control sequences for the expression of human interferon in Chinese hamster ovary (CHO) cells or progeny thereof. The human recombinant interferon so produced contains glycans which are a subset of the population of glycans which are contained in the native counterpart, and may be used in therapeutic formulations. The CHO cells yield high levels of human interferon with no detectable amounts of host IFN, either constitutive or inductive.