The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 23, 1990
Filed:
Aug. 07, 1987
Applicant:
Inventors:
Daniel J Capon, San Mateo, CA (US);
Richard M Lawn, San Francisco, CA (US);
Arthur D Levinson, Hillsborough, CA (US);
Gordon A Vehar, San Carlos, CA (US);
William I Wood, San Mateo, CA (US);
Assignee:
Genentech, Inc., South San Francisco, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P / ; C12N / ; C12N / ;
U.S. Cl.
CPC ...
435 696 ; 435320 ; 435 691 ; 4351723 ; 4352402 ; 435948 ; 935 32 ; 935 39 ; 935 56 ; 935 57 ; 935 70 ; 536 27 ; 530383 ;
Abstract
A method for producing factor VIII in recombinant mammalian host cells utilizing an expression vector containing a selectable marker DNA and an amplifiable marker DNA. The initial selection is based upon the selectable marker and subsequent amplification of factor VIII DNA and amplifiable marker DNA is conducted in cells not deficient in the amplifiable marker.