The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 11, 1990
Filed:
Jun. 03, 1987
Applicant:
Inventors:
Barbara P Wallner, Cambridge, MA (US);
Timothy A Springer, Newton, MA (US);
Catherine Hession, South Weymouth, MA (US);
Richard Tizard, Cambridge, MA (US);
Robert Mattaliano, Newton, MA (US);
Michael L Dustin, Boston, MA (US);
Assignees:
Biogen, Inc., Cambridge, MA (US);
Dana Farber Cancer Institute, Inc., Boston, MA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P / ; C12N / ; C12N / ;
U.S. Cl.
CPC ...
435 693 ; 43525231 ; 43525233 ; 43525234 ; 43525235 ; 435254 ; 4352402 ; 4352404 ; 4351723 ; 435320 ; 536 27 ; 935-1 ; 935 11 ; 935 12 ; 935 27 ; 935 32 ; 935 70 ; 935 71 ; 935 72 ;
Abstract
Polypeptides that bind to CD2, the receptor on the surface of T-lymphocytes. Most preferably, the polypeptides bind to CD2 on the surface of T-lymphocytes and inhibit adhesion between T-lymphocytes and target cells. DNA sequences that code on expression in appropriate unicellular hosts for those polypeptides. Methods of making and using those polypeptides in therapy and diagnosis.