The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 04, 1990

Filed:

Jun. 23, 1988
Applicant:
Inventors:

C Edgar Cook, Durham, NC (US);

Mansukh C Wani, Research Triangle Park, NC (US);

Y-W Lee, Chapel Hill, NC (US);

Jerry R Reel, Delmar, NY (US);

Douglas Rector, Raleigh, NC (US);

Assignee:

Research Triangle Institute, Research Triangle Park, NC (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C07J / ;
U.S. Cl.
CPC ...
514176 ; 514179 ; 514192 ; 514177 ; 514169 ; 552529 ; 552597 ; 552598 ; 552604 ; 552558 ; 552608 ; 552531 ; 552520 ; 552596 ; 552605 ; 552514 ; 552592 ; 552628 ; 552532 ; 540 54 ; 540 36 ; 540 37 ;
Abstract

A 11.beta.-aryl-19-norprogesterone steroid of the formula: ##STR1## wherein (i) R.sup.1 is H, C.sub.1-4 alkyl, C.sub.2-4 alkenyl, C.sub.2-4 alkynyl, OH, OC(O)CH.sub.3, or OC(O)R.sup.5, wherein R.sup.5 is C.sub.2-8 alkyl, C.sub.2-8 alkenyl, C.sub.2-8 alkynyl or aryl, R.sub.2 is H, R.sup.3 is H, C.sub.1-4 alkyl, C.sub.2-4 alkenyl or C.sub.2-4 alkynyl, R.sup.4 is H, CH.sub.3, F or Cl, R.sup.6 is H, (CH.sub.3).sub.2 N, CH.sub.3 O, CH.sub.3 CO, CH.sub.3 S, CH.sub.3 SO, CH.sub.3 SO.sub.2, and X is O or NOCH.sub.3 ; or


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