The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 28, 1990

Filed:

Apr. 28, 1986
Applicant:
Inventors:

Michael J Byers, Gwynedd, PA (US);

Eric G Isacoff, Richboro, PA (US);

John O Naples, Dresher, PA (US);

Assignee:

Rohm and Haas Company, Philadelphia, PA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N / ; C12N / ;
U.S. Cl.
CPC ...
43524025 ; 435243 ; 435180 ; 43524026 ; 435942 ;
Abstract

Nonanchorage-dependent cells are immobilized for cell culturing or the production of cell products, by contracting an aqueous suspension of the cells with a floc formed by the combination of positively and negatively charged ion exchange resins having particle sizes ranging from about 0.01 to about 1.5 microns. The flocs may be formed either prior to contract with the cells or may be formed in situ in the cell suspension upon separate addition of the resins, preferably by first adding the positively charged resin followed by the negatively charged resin. The resin floc operates as a microcarrier for the cells.


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