The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 28, 1990
Filed:
Sep. 06, 1989
Holger Schmeisser, Gottingen, DE;
Heinz-Gerhard Kohn, Dransfeld, DE;
Heraeus Sepatech GmbH, Osterode, DE;
Abstract
An improved method and apparatus for separating high-molecular-weight substances from cells suspended in liquid nutrient media, features continuous central monitoring and control of the process by a computer (22), and a way to combine the heretofore separate processes of first, separating media into solid and liquid components, and second, concentrating the proportion of high-molecular-weight components in the separated liquid. The media are conveyed by a first pump (3) to a centrifuge continuous flow rotor (2), which separates the solids from the liquid components and directs the latter to an intermediate reservoir (5), which sits on an electric scale (7) which is continuously monitored. From here they are fed to a filtration unit (9) in which the high-molecular-weight substances are separated and recycled through a feedback line (11), with the aid of a second pump (10), into the intermediate reservoir (5). The central computer and control unit (22) controls the centrifuge and pumps, monitors the scale (7) and pressure sensors (13), and adjusts the process parameters. An optical sensor (26) monitors the solids content at the centrifuge output (4).