The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 31, 1990
Filed:
Apr. 09, 1987
Applicant:
Inventors:
Richard Legoux, Caraman, FR;
Pascal Leplatois, Cuq Toulsa, FR;
Evelyne L Joseph, Saint Orens De Gameville, FR;
Brigitte Niaudet, Toulouse, FR;
Willem Roskam, Montgiscard, FR;
Assignee:
Societe Anonyme: Sanofi, Paris, FR;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P / ; C12N / ; C12R / ; C12R / ;
U.S. Cl.
CPC ...
435 694 ; 4351723 ; 4352523 ; 43525233 ; 4351721 ; 435 698 ; 935 41 ; 935 56 ; 935 60 ; 935 73 ; 935 61 ;
Abstract
The invention relates to a microbiological process for the preparation of a protein by culturing a mutant bacterial strain. This process consists in using a bacterial strain carrying a mutation which limits, or even suppresses, the expression of the operons whose transcription depends on the fixation of the cAMP-CRP complex, a DNA sequence coding for a protein precursor having been introduced into the said bacterial strain.