The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 24, 1990

Filed:

Aug. 10, 1988
Applicant:
Inventors:

Robert W Eisinger, San Diego, CA (US);

Mohammed H Khalil, San Diego, CA (US);

David H Katz, La Jolla, CA (US);

Robert B Sargeant, Ramona, CA (US);

Assignee:

Quidel, San Diego, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N / ;
U.S. Cl.
CPC ...
435-7 ; 435805 ; 435810 ; 436512 ; 436514 ; 436518 ; 436520 ; 436523 ; 436531 ; 436535 ; 436807 ; 436808 ; 436810 ; 422 55 ; 422 56 ; 422 57 ; 422 58 ; 422101 ;
Abstract

A method and apparatus for conducting specific binding pair assays, such as immunoassays, is described. A porous membrane capable of non-bibulous lateral flow is used as assay substrate; a member of the binding pair is affixed in an indicator zone defined in the substrate. The sample is applied at a position distant from the indicator zone and permitted to flow laterally through the zone; any analyte in the sample is complexed by the affixed specific binding member, and detected. A novel method of detection employs entrapment of observable particle in the complex. Blood is a particularly preferred sample as the red blood cells can be used as the observable particles for detection of the complex.

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