The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 17, 1990
Filed:
Nov. 28, 1988
Richard D Rotondo, St. Paul, MN (US);
Advanced Biologics, Inc., Minneapolis, MN (US);
Abstract
Hydropyridine analogs, dihydropyridine analogs, trihydropyridine analogs, hydropurine analogs, dihydropurine analogs, trihydropurine analogs, N,N,N,'-trimethyl- N'-(2-hydroxy-3-methyl-1,3-propanediamone analogs, 1-methyl-3-[N-(4-iodophenyl)- carbamoyl]-1,4-dihydropyridine analogs, that are lipid-soluble with the specific electron charge density and therefore useful for the administration of several compounds that need to penetrate the blood-brain capillary barrier. Once inside the brain these compounds undergo NAD-NADH reduction thereby providing for a brain serum retention. These compounds having been modified herein to deliver various compounds, some of which are those that are progressively absent during the course of a disease called Alzheimer's Disease.